Rozemarijn goed voor het haar

Rozemarijn is één van de planten, die traditioneel veel voor het hoofd en het haar (groei) gebruikt werd. Een recent onderzoekje lijkt dat nu te bevestigen.

Topical administration of Rosmarinus officinalis leaf extract (RO-ext, 2 mg/day/mouse) improved hair regrowth in C57BL/6NCrSlc mice that experienced hair regrowth interruption induced by testosterone treatment. In addition, RO-ext promoted hair growth in C3H/He mice that had their dorsal areas shaved. To investigate the antiandrogenic activity mechanism of RO-ext, we focused on inhibition of testosterone 5α-reductase, which is well recognized as one of the most effective strategies for the treatment of androgenic alopecia. RO-ext showed inhibitory activity of 82.4% and 94.6% at 200 and 500 µg/mL, respectively. As an active constituent of 5α-reductase inhibition, 12-methoxycarnosic acid was identified with activity-guided fractionation. In addition, the extract of R. officinalis and 12-methoxycarnosic acid inhibited androgen-dependent proliferation of LNCaP cells as 64.5% and 66.7% at 5 µg/mL and 5 μM, respectively. These results suggest that they inhibit the binding of dihydrotestosterone to androgen receptors. Consequently, RO-ext is a promising crude drug for hair growth.

Promotion of Hair Growth by Rosmarinus officinalis Leaf Extract Kazuya Murata1, Kazuma Noguchi1, Masato Kondo2, Mariko Onishi2, Naoko Watanabe2, Katsumasa Okamura2, Hideaki Matsuda1,* Phytotherapy research

Andere kruiden voor de gezondheid van het haar zijn o.a. brandnetel en Oost-Indische kers. Lees meer op mijn website https://sites.google.com/site/kruidwis/fytotherapie/haargroei